PDO Threads for Hair Growth – ISHRS 2025, Berlin
Dr. Alan J. Bauman, MD, ABHRS, FISHRS

Poster & Abstract

Evaluation of Hair Growth Stimulation via Polydioxanone (PDO) Thread Application: An Observational Pilot Study
Presented at the 33rd Annual ISHRS World Congress, Berlin (2025)

Disclosures:

None

Download Poster:

https://www.baumanmedical.com/wp-content/uploads/2025/10/ISHRS2025_PDO_Hair_Growth_AJBauman_V4.pdf

Read Accepted Abstract Text:

https://www.baumanmedical.com/wp-content/uploads/2025/10/PDO_Threads_Hair_Growth_Abstract_SHRS_2025_AJBauman.pdf

Study Summary

Objective: Assess safety and efficacy of PDO threads in stimulating hair regrowth in men and women with androgenetic alopecia (AGA).

Methods: PDO threads (29g, 25–38mm) placed in subcutaneous scalp plane; outcomes measured via global photography, trichoscopy, and Hair Mass Index (HMI).

Results: All patients showed improved density and coverage. One case: +48% HMI at 12 weeks.

Conclusion: PDO threads are a promising, minimally invasive regenerative therapy, suitable as standalone or adjunct to existing hair restoration modalities.

Mechanism of Action

PDO threads stimulate local tissue remodeling and angiogenesis through:

• Extracellular matrix (ECM) scaffold effect
• Neo-collagenesis and fibroblast activation
• Improved local vascular supply
• Growth factor modulation (↑ FGF-7, ↓ FGF-5)

Training & Clinical Application

For physicians seeking to integrate PDO threading into clinical practice:
PDOgro™ Physician Training Program

Watch PDOgro Webinar

Media & Press

For interviews, media inquiries, or press kits:
Press Release & Media Contact: pr@baumanmedical.com or lanny@em50.com

About Dr. Bauman

• Founder & Medical Director, Bauman Medical, Boca Raton, FL
• ABHRS-Certified Hair Restoration Surgeon
• 28+ years, 34,000+ patients treated
• Recognized as one of the world’s top hair transplant surgeons

References

Middleton JC, Tipton AJ. Synthetic biodegradable polymers as medical devices. Qmed.com. 1998. Available from: https://www.qmed.com

Shin HJ, Jeong HS, Shin HJ, et al. The success of thread-embedding therapy in generating hair re-growth in mice points to its possibly having a similar effect in humans. J Pharmacopuncture. 2015;18(4):20-25. doi:10.3831/KPI.2015.18.033

Bharti S, Sonthalia S, Patil P, Dhurat R. Scalp threading with polydioxanone monofilament threads: a novel, effective and safe modality for hair restoration. J Eur Acad Dermatol Venereol. 2017;31:e476-e513. doi:10.1111/jdv.14403

Bharti J, Patil P. Polydioxanone threads in androgenetic alopecia: A novel innovation. Presented at: 12th International Conference and Exhibition on Cosmetic Dermatology and Hair Care; Nov 28–30, 2016; San Antonio, TX.

Yoon JH, Kim SS, Oh SM, Kim BC, Jung W. Tissue changes over time after polydioxanone thread insertion: an animal study with pigs. J Cosmet Dermatol. 2019;18(3):885-891. doi:10.1111/jocd.12718

*Each individual's treatment and/or results may vary