PDO Threads for Hair Growth – ISHRS 2025, Berlin
Poster & Abstract
Evaluation of Hair Growth Stimulation via Polydioxanone (PDO) Thread Application: An Observational Pilot Study
Presented at the 33rd Annual ISHRS World Congress, Berlin (2025)
Disclosures:
None
Download Poster:
https://www.baumanmedical.com/wp-content/uploads/2025/10/ISHRS2025_PDO_Hair_Growth_AJBauman_V4.pdf
Read Accepted Abstract Text:
Study Summary
Objective: Assess safety and efficacy of PDO threads in stimulating hair regrowth in men and women with androgenetic alopecia (AGA).
Methods: PDO threads (29g, 25–38mm) placed in subcutaneous scalp plane; outcomes measured via global photography, trichoscopy, and Hair Mass Index (HMI).
Results: All patients showed improved density and coverage. One case: +48% HMI at 12 weeks.
Conclusion: PDO threads are a promising, minimally invasive regenerative therapy, suitable as standalone or adjunct to existing hair restoration modalities.
Mechanism of Action
PDO threads stimulate local tissue remodeling and angiogenesis through:
- Extracellular matrix (ECM) scaffold effect
- Neo-collagenesis and fibroblast activation
- Improved local vascular supply
- Growth factor modulation (↑ FGF-7, ↓ FGF-5)
Training & Clinical Application
For physicians seeking to integrate PDO threading into clinical practice:
PDOgro™ Physician Training Program
Media & Press
For interviews, media inquiries, or press kits:
Press Release & Media Contact: pr@baumanmedical.com or lanny@em50.com
About Dr. Bauman
- Founder & Medical Director, Bauman Medical, Boca Raton, FL
- ABHRS-Certified Hair Restoration Surgeon
- 28+ years, 34,000+ patients treated
- Recognized as one of the world’s top hair transplant surgeons
References
Middleton JC, Tipton AJ. Synthetic biodegradable polymers as medical devices. Qmed.com. 1998. Available from: https://www.qmed.com
Shin HJ, Jeong HS, Shin HJ, et al. The success of thread-embedding therapy in generating hair re-growth in mice points to its possibly having a similar effect in humans. J Pharmacopuncture. 2015;18(4):20-25. doi:10.3831/KPI.2015.18.033
Bharti S, Sonthalia S, Patil P, Dhurat R. Scalp threading with polydioxanone monofilament threads: a novel, effective and safe modality for hair restoration. J Eur Acad Dermatol Venereol. 2017;31:e476-e513. doi:10.1111/jdv.14403
Bharti J, Patil P. Polydioxanone threads in androgenetic alopecia: A novel innovation. Presented at: 12th International Conference and Exhibition on Cosmetic Dermatology and Hair Care; Nov 28–30, 2016; San Antonio, TX.
Yoon JH, Kim SS, Oh SM, Kim BC, Jung W. Tissue changes over time after polydioxanone thread insertion: an animal study with pigs. J Cosmet Dermatol. 2019;18(3):885-891. doi:10.1111/jocd.12718